“Computational cellphone microscopy” by Arpa, Wetzstein, Lanman and Raskar

Within the last few years, cellphone subscriptions have widely spread and now cover even the remotest parts of the planet. Adequate access to healthcare, however, is not widely available, especially in developing countries. We propose a new approach to converting cellphones into low-cost scientific devices for microscopy. Cellphone microscopes have the potential to revolutionize health-related screening and analysis for a variety of applications, including blood and water tests. Our optical system is more flexible than previously proposed mobile microscopes and allows for wide field of view panoramic imaging, the acquisition of parallax, and coded background illumination, which optically enhances the contrast of transparent and refractive specimens.

1. Breslauer, D. N., Maamari, R. N., Switz, N. A., Lam, W. A., and Fletcher, D. A. 2009. Mobile Phone Based Clinical Microscopy for Global Health Applications. PLoS ONE 4, 7 (07), e6320.
2. Smith, Z. J., Chu, K., Espenson, A. R., Rahimzadeh, M., Gryshuk, A., Molinaro, M., Dwyre, D. M., Lane, S., Matthews, D., and Wachsmann-Hogiu, S. 2011. Cell-phone-based platform for biomedical device development and education applications. PLoS ONE 6, 3 (03), e17150.
3. Tseng, D., Mudanyali, O., Oztoprak, C., Isikman, S. O., Sencan, I., Yaglidere, O., and Ozcan, A. 2010. Lensfree Microscopy on a Cellphone. Lab Chip 10, 1787–1792.
4. Zhu, H., Yaglidere, O., Su, T.-W., Tseng, D., and Ozcan, A. 2011. Cost-effective and compact wide-field fluorescent imaging on a cell-phone. Lab Chip 11, 315–322.