“Molecular Dynamics of Membrane Protein and Receptor Protein Binding” by Westbrook

Conference:

• SIGGRAPH 1992
• More from SIGGRAPH 1992:  

Title:

Molecular Dynamics of Membrane Protein and Receptor Protein Binding

Program Title:

Showcase

Presenter(s):

• Edwin Westbrook

Collaborator(s):

• Christina Vasilakis

Project Affiliation:

Argonne National Laboratory and University of Illinois at Chicago

Description:

This project uses computer graphics to develop an understanding of structural biology dynamical processes. The graphics illustrate the probable means by which cholera toxin transports an intact protein through a target cell’s external membrane while intoxicating the cell. In this process, cholera toxin recognizes and binds an external membrane-bound receptor, triggering a dynamic change in the structure of the toxin and the membrane; a portion of the toxin and enzyme enter the cell.

Type:

E-Tech