“Discovering biostructure constraints using VRML visualization” by Ray and Ozer

The determination of a biomolecule’s complete 3-dimensional structure provides invaluable information about the molecule’s function, and how that function might be modulated. This in turn leads to insights across the biological spectrum. Unfortunately, determining protein or nucleic-acid structures from the molecules themselves is difficult due to physical impediments. Likewise, accurate computational prediction of such structures from physical principles remains computationally intractable due to the overwhelming number of degrees of freedom in the system.

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