“Decomposing non-rigid cell motion via kinematic skeletonization”




    Decomposing non-rigid cell motion via kinematic skeletonization


    Considering that most cells have an intricate spatial organization to their components and biological processes, it is beneficial to express sub-cellular positions and displacements in coordinates relative to the enclosing cell. This spatial context is often more meaningful than that of the microscope field of view in which a cell is observed. However, defining such a cell coordinate system can be difficult for cells which are moving rapidly and changing shape, requiring that one define a moving frame of reference to which measurements can be transformed.


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    2. Wilson, C. A., and Theriot, J. A. 2006. A correlation-based approach to calculate rotation and translation of moving cells. IEEE Trans Image Process 15, 7, 1939–51.

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