“Influencing Bone Remodeling in Osteoporosis” by Hurd
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Conference:
- SIGGRAPH 2003 More animation videos from SIGGRAPH 2003:
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SIGGRAPH Video Review:
Track:
- 10
Title:
- Influencing Bone Remodeling in Osteoporosis
Length:
- 3:55
Director(s):
Company / Institution / Agency:
- Hurd Studios
Description:
Physician education on osteoporosis and the mechanism of action of Actone1®,a drug for its treatment. Bone is living tissue that is constantly renewed. Cells Called osteoclasts remove damaged bone, and cells called osteoblasts replace it with new bone. Because estrogen suppresses osteoclast activity, postmenopausalestrogen loss causes an imbalance in favor of the osteoclast, that is, bone removal. When more bone is removed then replaced, bone thinning causes osteoporosis. Actonel is absorbed by bone and ingested by osteoclasts during bone removal. By interfering with cell function, Actone kills osteoclasts.Remodeling balance is restored and osteoporotic fracture risk is reduced.
Additional Contributors:
Screenwriters: Jane Hurd, Christine Young
Animators: Donald Tolentino, Jason Guerrero, Andy Wagener, Donna DeSmet
Title Design: Luba Proger
