“Molecular Dynamics of Membrane Protein and Receptor Protein Binding” by Westbrook – ACM SIGGRAPH HISTORY ARCHIVES

“Molecular Dynamics of Membrane Protein and Receptor Protein Binding” by Westbrook

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Conference:


Type(s):


Title:


    Molecular Dynamics of Membrane Protein and Receptor Protein Binding

Program Title:


    Showcase

Organizer(s)/Presenter(s):


Collaborator(s):


Project Affiliation:


    Argonne National Laboratory and University of Illinois at Chicago (UIC)

Description:


    This project uses computer graphics to develop an understanding of structural biology dynamical processes. The graphics illustrate the probable means by which cholera toxin transports an intact protein through a target cell’s external membrane while intoxicating the cell. In this process, cholera toxin recognizes and binds an external membrane-bound receptor, triggering a dynamic change in the structure of the toxin and the membrane; a portion of the toxin and enzyme enter the cell.


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